Gefitinib-induced paronychia: response to autologous platelet-rich plasma

SH Kwon, JW Choi, JS Hong, SY Byun… - Archives of …, 2012 - jamanetwork.com
Background Paronychia has been reported in as many as 10% of patients treated with
gefitinib. Although conservative management and treatment with topical or systemic
antibiotics are beneficial, no effective method exists for intractable cases. Platelet-rich
plasma (PRP) consists of a high concentration of platelets that promote wound healing
through chemotaxis, cell proliferation, angiogenesis, and tissue remodeling. Observations
We herein report a refractory case of gefitinib-induced paronychia successfully treated with …
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